Any fan of the Ultimate Universe know's it's had it's share of sloppy continuity and retcon's. First thing that Springs to mind is most of the Ultimate Team Up series which was one of the debut comic lines for 1610 was retconned. Then you have things like Van Damme's cloven feet and reversed legs being forgotten about, along with the fact that it's explicitly said and proven that he is the physical superior to Ben Grimm only to have Ben later beat him to death. I could go on for a while about all the little things retconned, changed, or forgotten about in the ultimate universe. I think though, most of all, Iron Man has gotten the short end of the stick.
Love the books or hate them, Iron Man had two entire volumes of "origin" story retconned. Along with them Stark's superhuman healing which was featured in awesome stories like Ultimate Human seems to be gone as well. He had his unique 1610 armor design forgotten about for years. Now it seems they've forgotten his name. Since his debut his name has been Antonio Stark in the Ultimateverse, not Anthony. However, with Ultimate Comics Iron Man I, it seems they've forgotten even this. It saddens me. That said I did enjoy the first issue of Ultimate Comics Iron Man. Just wanted to rant about how I wished they'd keep his continuity a bit tighter.