Who is Spider-man's greatest nemesis?

Before this discussion even begins, lets imagine that the events of ASM 700 happened, but Peter Parker kept his body and Superior Spider-man never happened Throughout the extensive tenure of Spider-man who I would be considered the ying to his yang?

1. Green Goblin (Norman)

2. Doc Ock

3. King Pin

4. Venom

5. Hob Goblin

6. Kraven

7. Carnage

8. Vulture

9. Scorpion

10. Smythe

Well, Doc Ock did kill him. But I want to say Green Goblin.

Doc Ock

This or anyone who knows his true Identity

Doctor Octopus.

Norman is a punk who got a lucky and was retroactively made more important.