For Nigh Top-tier levels:
Neo -granted he has his Matrix capabilities outside of the Matrix.
Final Fantasy characters
Stephen Chow's character in Kung Fu Hustle
I wouldn't go with Anime characters now as that will be too plentiful.
For street levelers:
Solid Snake
Universal Soldier/s
Predator/s, Terminator/s and Robocop (though they already had comic incarnations)
Tom Clancy characters: John Clark, Sam Fisher, Rainbow Six, Ghost Recon, etc.
As what was said by an earlier post, Jason Bourne
Any Bruce Lee character (especially Chen Zen, he seems to be the most "superhuman" of all his characters).
The Expendables
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