Best Marvel Comics two character tie up?

So Superman and Batman are gonna be in a film. What would be the best Marvel duo do you reckon? Iron Man and Hulk could work, but I'd love Spiderman and Hulk, personally.

1. Thor and the Silver Surfer

2. The Punisher and Dead Pool

3. Doctor Strange and Ghost Rider

4. Blade and Moon Knight

5. Spiderman and Wolverine

Nick Fury(Samuel L Jackson) and Nick Fury(David Hasselhoff)