IMHO, the best = Heath Ledger/Joker, I honestly don't care for Joker as a character but this was easily the best film adaptation of a comic character.
Worst = Ryan Reynolds/Deadpool, honestly I don't think there is a worse version of Deadpool possible. A character that's known for his mouth has no mouth??? Deadpool has claws and laser vision all of a sudden and his body color and look was completely idiotic.
What do you think??