Are there any must read marvel comics in general ?

Thanks

@90mv: Avengers #1

Avengers,New Avengers, Superior Spider Man.

Daredevil Born Again

Whedon's Astonishing X-Men and Millar's Ultimates come to mind.

Do you mean the universe as a whole? Or for specific characters? Because there are must-reads for nearly every major Marvel character. Here are a number that spring to mind:

Marvel Universe as a whole: Infinity Gauntlet, Civil War, Secret Wars

Cosmic: Annihilation, Death of Captain Marvel

Spider-Man: Steve-Ditko-Romita run, Kraven's Last Hunt, The Death of Jean DeWolffe

Avengers: Kree-Skrull War, Operation Galactic Storm, Busiek-Perez run

Captain America: Captain America No More, Mark Waid's run, Ed Brubaker's run

Iron Man: Extremis, Demon in a Bottle, Armor Wars

Thor: Walter Simonson's run, J. Michael's run, Kirby's run

Incredible Hulk: Peter David's run, Future Imperfect, Planet Hulk

Fantastic Four: Lee-Kirby run, John Byrne run, Hickman's run

Dr. Strange: Ditko run, Oath, Triumph/Torment

Daredevil: Born Again, Miller's run, Ed Brubaker's run, Bendis' run

X-Men: Claremont's run, Whedon's run, God Loves, Man Kills

Wolverine: Claremont-Miller run, Weapon X, Origin

Punisher: Ennis' MAX run, Born, Welcome Back Frank

Ultimate Universe: Ultimates/Ultimates 2, Millar's run on Ultimate X-Men, Bendis' run on Ultimate Spider-Man

Ed Bunker's Captain America, and Mark Miller's Civil War.

Captain America (Brubaker Run) and Winter Soldier (Brubaker run.) (Latour run on Winter Soldier as been great to. It has 2 issues left.)

Avengers (Hickman has been great.)

Punisher (Greg Rucka run) (His run is a must read for any Punisher fan.)

regardless of what people say the marvel now Captain America is Awesome!

Planet Hulk

Millar's Ultimates

Fraction's Iron Man

House Of M

Spider-Man Blue