Ok, whoever watches Supernatural will know what The Colt is. It's a specially made gun by the demon hunter Samuel Colt, and takes a special type of bullet. It can also take normal bullets, but the bullets it was specially designed for can kill anything Supernatural with one shot, as long as it's in a place where it could kill them.
For example, Most Demons can't be killed easily. But, if you shot one say in the head or in the heart with one of these bullets, it would kill them. But, if you hit them in a leg, it would most likely really hurt. Like bad.
So, the question is, Can The Colt Kill the King of Demons?