Hmmm, SuperG uses her x-ray vision, heat blasts Sue until Sue can't handle it anymore, super girl either continues to heat beam her, or fly over to sue in the blink of an eye and snap her neck before Sue can blink. Sorry, I like both, but Super Girl has this one easy.
Supergirl easily. Invisible Woman turning as her name suggests, invisible, won't cause a problem to Supergirl as her other senses can detect IW. She can easily break through her FFs. IW FFs won't be able to break Supergirl from the inside because of her invulnerability. Of course, this is assuming that Supergirl doesn't take her out as soon as the battle starts.
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