Piccolo was powerful enough to blow up moons and other large celestial bodies before he fused with Kami. Sesshomaru would get stomped if he stepped to Piccolo.
i dont know i like both but i think that Sesshōmaru has a chance just because all of his demon powers and aweasome sword
Piccolo Jr. has insane regeneration abilities and is obviously more powerful and skilled at combat than Sesshomaru. He wins this with great ease.
I don't think he can withstand a full powered punch from Piccolo to be honest, let alone one energy blast!
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