Blade's got the speed, weapons, and tech to take down Sabretooth. His standard weaponry of his acid-edged sword, stake shotgun, pistols, and his cable-daggers can make a serious dent. While his shotgun and pistols may not overcome Sabretooth's healing factor, they can still still make an impact. His sword can easily decapitate Sabretooth, who did not have an adamantium skeleton. Sbaretooth may be stronger, but Blade has beaten foes stronger than himself and smarter than Sabretooth, namely the Reaper from the second Blade movie and Dracula in the third. Blade also fights vampires as skilled in combat as himself, and Sabretooth is more a brawler than a trained fighter, savoring in overpowering foes. While Sabretooth is no pushover, I think Blade will overcome him through speed, fightinging techinque, and weaponry. The vampires have also shown to have a degree of healing factor, and Blade has shurgged off heavy blows. If he can manage to bite Sabretooth and go "bloodlusted" so to speak, it would more than likely be in the bag. As a vampire, he can also fight in the dark better than Sabretooth likely could, since this fight takes place at night. Blade gets my vote with a win about 7/10 times in my opinion. Just my two cents.
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