Peter parker VS Edward Elric
spiderman, edward elric would be hard pressed to try to even hit him. spider-sense, super agility, and super strength is too much for poor short ed to handle, after all, ed is only a simple human and he had a hard time fighting that xing girl who was lings(not sure what his name was, havent read it in a long time, the emperor boy) bodyguard and she wasnt as agile or as fast as spiderman.
Spiderman all day everyday. His spider sense is the key factor here. Anything edward do....spiderman's precog will give him the warning regardless of where the attack is coming from. And add in spiderman reflexes, speed, and strength...he should beat ed anytime he gets ready