Deathstroke (new 52)
Slade has his armor, sword, 2 knives, his pistol with 5 clips of hollow point bullets, an AK-47 with 2 clips of hollow points, and 5 concussion grenades.
Spiderman knows Deathstroke is a dangerous murderer and assassin.
Deathstroke knows Spiderman is a dangerous, powerful metahuman.
Spiderman will kill Slade if necessary, but bloodlust is not on.
Deathstroke has been sent to kill somebody in NYC, until Spiderman gets in his way.
Fight starts in a small parking lot outside a gas station in NYC. No bystanders.
Win by KO or death. Incapacitation via webbing is not allowed.