Lizard got downed by a few swat with guns. Cap wiped the floor with several armed and armored Hydra agents using advanced weaponry without getting a scratch. I think Cap could solo.
In all fairness, Lizard was surrounded by like 10-15 swat members in an enclosed space with automatic weapons. There was no where for him to go, and he's pretty large anyway. Plus he regenerated pretty much instantly.
Cap is much faster, much more skilled, and possibly close to Lizard in strength. I'd put movie Cap over movie Spiderman based on feats. I think he'd take lizard out, a good shield shot to the face.
I agree with Cap being faster, and more skilled, but I don't think they're close in strength. I'm pretty sure Lizard was tossing around cars at one point. Aside from curing him, I don't think the team can keep him down. Spider-man was having major issues with him and he's above Cap in everything except skill. If the team decides to go h2h then they'll get caught at some point and wrecked.
won't help him much. Spiderman in the movie exceeded pretty much all of Cap's stats, and even with prep the Lizard beat him a few times and almost killed him as well. Cap may cause trouble but he doesn't have a weapon that will put down Lizard.