@w0nd: Infamous Second Son was a bit confusing in terms of durability but they sure as hell can easily take on armies. Evident by Cole's found information of Bertrand and his sales of Vemaak and Corrupted. Conduits are a legitimate threat.
What I really talk about is that Alex has never been introduced to conduit abilities. That means he won't be able to adapt to it. His experience with it would probably get him killed since he never knew that it existed. A foreign alien energy that he doesn't even know exists. The reason why he's so low in terms of resistance against conduit elements is that. The conduit bosses had seven years of training and had their own unique powers, not copy powers but their own. The Dup mooks probably only have fewer training or like the Vemaak are unsuited to the power. Some Dup soldiers can't be taken down easily but they're also one of the few that were stronger than the others.
And killing yourself with your own power? Guess Alex can also die to bullets huh. There are limitations to gameplay mechanics. Or that's just an assumption that Delsin can get injured by his own attacks, or keep hitting himself with the same attacks by accident and killing himself.
Really, in the end, no matter what, flesh is organic. Biomass is organic. Biomass if still flesh. Considered animal flesh too. Sure might be some differences but in the end it'll be affected the same way by Delsin's powers. Really, it makes no difference. Alex is still technically skin naked to the powers Delsin has.
And reason why Delsin easily beats Fetch is because he absorbed every neon source around her and attacked her with it instead of letting her do it. Do remember Fetch seemed high on that battle too so that could be why she wasn't draining the neon to heal herself. Even then she still had a lot of resistance to shrug off neon. If you consider the health bar that at least.
And if Alex is so damn heavy to create those huge craters on landing, then how the hell can he jump so high and glide without losing so much blood? Because if he wanted to go that fast flying he'll have to use up so much blood? Or why is it that he easily gets knocked around by blunt attacks from Supreme Hunters or Hunters when he could adapt to those? Or his shield being a default ability and never gaining anything to adapt against the rockets that constantly knock you down fired from everywhere?
Also, another thing for headshot no kill bosses, Gameplay mechanics. To make the game harder so you can't oneshot everyone and win the game. Because it provides no challenge and infamous is known for its challenge. Hell you can easily zap the head off a Corrupted Ravager on infamous 2 if you're pinned down but not when you're standing.
Really, gameplay mechanics are a fickle thing