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A trip to the Negative Zone goes awry when Annihilus shows up to make trouble. Reed and crew are locked in a battle for their very lives against a foe whose powers just might surpass their own. And it's all part of Reed's plan.  
Now, the FF have the DNA samples and plan to use them to round up their foes once and for all. If they succeed, they will need a place to put the villains, hence Reed's current plan to build a new version of the Vault inside the Negative Zone. In order to achieve this goal, Reed enlists the aid of Andrew Lewis, the original designer of the Vault. Reed then takes the rest of the FF into the Negative Zone to scout out locations for the prison. There, they encountered not one but two versions of their deadly foe, Annihilus. Back on Earth, an excited Andrew ran home to tell his wife the good news. She informed him that she was busy reading the paper.

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