I have really enjoyed the Exiles over the last couple years. Along with Bendis' "Powers" series it has been the ish i most look forward to each month.
Sure it may rip itself directly from quantum leap, but the cast of characters are always pretty colorful. Plus the alternate universe thing allows the writers to bend storylines outside of the continuity.
My favorite issues were the ones where Tony Stark had killed off Dr. Doom and took on his cape and mantle, becoming an evil character. He had killed off Reed Richards I believe and Sue Storm ended up marrying Black Bolt of the inhumans, which I thought was a pretty awesome fit.
What's your favorite universe from the exiles?