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Greer Nelson (née Grant) first appeared as The Cat in the comic of the same name. She later became Tigra through a mystic ritual that bound the soul of one of the Cat People to her own.
Sara Wolfe was the secretary of Doctor Strange and the love interest of Dr. Strange's assistant, Wong.
Flaming Star is a medicine man of the Sioux tribe.
As a child, Matt Murdock was blinded by radioactive waste while trying to save an elderly stranger about to get hit by a truck carrying the dangerous material. In turn, his other senses were heightened to superhuman sharpness and he gained a form of "radar sense". By day, he is a successful trial lawyer; but by night, he guards Hell's Kitchen as Daredevil: the Man Without Fear.
A gunfighter from the Wild West in the Marvel Universe.
A Russian soldier who rescued an infant from a burning building during the Battle of Stalingrad, Ivan later became the guardian of the young child, Natasha Romanoff.
A 19th century bounty hunter who owed a debt to the Devil (possibly Mephisto in disguise). He was condemned to capture 50 souls of the Devil's choice or else condemn his own soul to torment. He was to capture Johnny Blaze, but failed to do so.
A former member of the Circus of Crime, Griffin is a gamma-irradiated member of the Gamma Corps.
Null is a horrible monster born from the despair of an extinct race.
Manticore was the enemy of Ghost Rider, Hawkeye, and the Two Gun Kid, he was captured and put into prison.
A fake psychic for the Quentin Carnival.
Live Wire was a member of the Circus of Crime. He uses an electrified lariat as his weapon of choice.
Luigi and his brother Ernesto are the Flying Gambonnos in the Circus of Crime.
Bruto the Strong Man of the Circus of Crime.
Sassafras is the pet dog of Beast and the New Defenders
Moondark is a mystic villain that has come into conflict with various heroes including Spider Man, Ghost Rider, Jack Russel and Night Rider.
God Ruler of the other Native American Gods.
An enemy of the Ghost Rider
A fellow biker that Johnny Blaze ran into on the road.
Owner of a Hollywood studio
Former leader of the Apache tribe, Mr. Littletree possesed the power to control any snake and was also immune to snake's venom.
One of Daredevil's first enemies who eventually reformed and became one of his supporters.
Member of the Circus of Crime.
Cloud is a nebula that took human form, and upon arriving on Earth was brainwashed by the Secret Empire. During a battle with the Secret Empire, the Defenders rescued Cloud and he/she joined the team.
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