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Reprint of Amazing Fantasy #15, Amazing Spider-Man #s 1-20, and Amazing Spider-Man Annual 1. Included are the first appearances of Spider-Man, Aunt May, Uncle Ben, Chameleon, Vulture, Tinkerer, Doctor Octopus, Sandman, Lizard, Living Brain, Electro, Enforcers, Big Man, Ox, Montana, Fancy Dan, Mysterio, Green Goblin, Kraven the Hunter, J. Jonah Jameson, Liz Allen, Flash Thompson, Betty Brant and Scorpion.
While attending a demonstration in radiology, high school student Peter Parker was bitten by a spider which had been exposed to radioactive rays. Learning he had gained great spider-like powers, Parker donned a costume and became the Amazing spider-Man. The tragic death of his Uncle Ben -- A death that could have been prevented -- taught Spider-Man that he must use his powers responsibly, and on that day a true hero was born!