1.) Marvel showed us a picture of him dead.
2.) Based off of the characters in the pic Anti-Venom is the only one eligible for a so called "Ultimate Sacrifice"
3.) Anti-Venom's primary power is healing and i think he is the only one with the potential to "heal" everyone from the spider crisis via an "Ultimate Sacrifice".(Reed Richards could cure everybody with his brilliant mind and resources but what fun would that be :P.)
4.)Not all Eddie Brock fans are happy with the whole Anti-Venom thing so maybe this could ultimately lead back to brock becoming Venom again.... :) :) :)
If this is ultimately the case ill just say I really enjoy or enjoyed the whole Anti-Venom thing it gave Brock another chance to stretch his muscles a bit but I would rather prefer Brock as the sick twisted self righteous Anti-Hero known as "Venom The Lethal Protector" once more. He would be returning to the role of Spider-Man's Most dangerous adversary once again and It would let the new generation see why he has become as popular as he was in the early nineties and nostalgia to the old venom fans such as myself. I wouldn't have to explain to people that he used to have Spider-Man more nervous than someone on their first day in prison. He would be tormenting Peters personal life and outclass Spider-man in there physical confrontations once more. He will just return to his role as Hokage Level Villain :P (yea im a Narutard also), However, I don't think the whole Anti-Venom concept should be dropped. As its design is awesome and it has potential, maybe it should find a new host and continue its cleansing crusade and become a full time ally of Spider-man or even Eddie Brock if he returns to his role as Venom. To me as spider-man is cool wearing the black suit he will never wear it forever and thats the exact same way i feel about Eddie as Anti-Venom. I don't necessarily have a problem as Flash as the current host of Venom as he using venom in a way that hasn't been done before as its an exciting and fresh take on both characters but in the words of Dormammu from the nineties Spider-man cartoon " The Symbiote could have bonded with anyone but only the rage and frustration of Eddie Brock could have created Venom." AMEN LOL.