Deadpool

The Watchtower leader who took on Cable, Deadpool, and the X-Men.

Ajax tormented Deadpool at the Weapon-X hospice. He was thought killed by Deadpool, but returned, only to be truly killed by Deadpool.

Angela del Toro is an ex-FBI Agent who worked on the Daredevil case. She became the White Tiger after the death of her uncle, Hector Ayala, the previous White Tiger, when she inherited his Jade Amulets.

Wisconsin's most famous super model, Ashley Crawford possesses the mutant ability to transform from trim and svelte to remarkably obese and back through regurgitation.

A Deadpool and Agent-X foe. He switched their bodies causing Deadpool to be Agent-X.

A teleporter who is on the Exiles.

Kidnapped (or liberated) from his post at a Hydra base by the mercenary Deadpool, Bob is a surprisingly normal guy. Deadpool's feelings for Bob range from friendship to considering him a pet.

A U.S. army sergeant was discharged and put into jail became one of the strongest members of The Wrecking Crew.

deadpool was offered to fight him

Doctor Bong is a former journalist, now mad-scientist with an unhealthy obession for Beverly Switzler, whom he met in a life-drawing class.

Domino is a skilled marksman and combatant. She also possesses the mutant ability to manipulate probability in her favor, giving the effect of incredible luck.

Eric O'Grady is Ant-Man. He just became a member of Norman Osborn's undercover strike team the Thunderbolts.

Though a member of Magneto's Acolytes, Cortez often rebelled against him, and was finally killed by Magneto.

A cybernetically enhanced member of the Six Pack.

Able to make her body malleable

Norman captured information that Deadpool was sending to Nick Fury on how to kill a Skrull Queen.

Henry is Punisher's hacker during Dark Reign.

Deadpool fought him to get his blood for a cure to his healing problem.

The son of Juggernaut from Earth-982, aka MC2 universe

Chris was sent to the store and when Chris returned he found Deadpool hunched over his father's badly burned body. After finding out who was his father's real killer (Maxi Milions), he still blamed Deadpool for his father's death because Deadpool failed to kill Maxi before the murder.

Loki is the Asgardian god of mischief and the adopted son of Odin. His arch enemy is Thor. As of late, Loki is now a she. Loki had involved Deadpool in his schemes against Thor.

Disturbed man, who is trying to make everyone see that the universe does not make sense. He has amazing recuperative powers and can make people act euphoric and reckless.

A fighter with low-level telepathy that read opponents moves to come out victorious. Mister X has mastered every fighting style known to man.

Deadpool has pwned Mr. Immortal many times. Many, many times.

Best known as the Green Goblin, one of Spider-Man's greatest enemies. Norman has the world fooled into thinking he is simply a business leader. He has recently shut down S.H.E.L.D., outed many heroes as cowards, and is now posing as the "Hero" Iron Patriot of the new Dark Avengers.

Deadpool was hired by Nick Fury to learn how to kill the Skrull Queen, Deadpool succeeded and tried to send the data to Fury, but it was intercepted by Norman Osborn, who killed the queen himself, ending the Secret Invasion and starting Dark Reighn at the same time.

Deadpool shrunk Rhino down into the size of a keychain via Pym particles. Rhino wanted revenge and sought to have Deadpool shrunk. Rhino then took him to a bar and showed him off where Deadpool was able to beat everyone up including Rhino.

Sabretooth is usually an enemy of Wolverine but has fought Deadpool before. One time he brought Deadpool back to Weapon X. Sabretooth ended up killing Copycat so Deadpool got revenge. Sabretooth then tried to take people hostage the Providence and Deadpool came and saved them by shooting Sabretooth an untold amount of times.

A longtime member of Alpha Flight, he gained his powers while trying to duplicate the conditions that created the Hulk.

Forced to drain the life force of others to sustain himself, Karl Lykos lives a miserable existence. If his victim happens to be a mutant, the drained force sets off a terrifying transformation.

Senyaka is from Sri Lanka, was a part of Acolytes and has energy-based whips.

S'Met'Kth was a tentacled alien who had the power to make every being in a planet overwhelmed with joy. Leaving behind mindless shells of said beings. The Messiah could also take over the bodies of beings that could act as his avatars, such as Captain America.

Squirrel Girl is a dangerous opponent that always seems to be under-estimated by her adversaries. Thanks to that she has defeated villains such as Doctor Doom, Thanos, Deadpool and MODOK among others.

tricked them into making copies of deadpool but didnt make them cancer free

Able to change shape

Thanos refuses to let Deadpool die so that he can not be with Death, because both Deadpool and Death were in love with each other.

Once a small-time crook, Parker Robbins is now the leader of his own crime syndicate. His cloak and boots give him supernatural powers from the mystic Dormammu.

Lonnie Lincoln used to be your run-of-the-mill hitman until one day he was locked in an airtight chamber filled with experimental gas, Diox-3, at the Osborn Chemical Plant.

Typhoid possessed an odd fixation with Deadpool for a short time after he freed her from a psyche ward.

Venom the alien symbiote that enhanced Spider- man's powers before he released the damage it was doing to his psyche. Other hosts have been called Venom such as Eddie Brock, and now Mac Gargan.

Widdle Wade is a dwarfed clone of Deadpool, and could only speak Japanese. He also had a pet lab dog named Daruma that he cared for very much.

Founder of the Wrecking Crew, Garthwaite was committing crime with a crowbar, when he haphazardly robbed a hotel room occupied by a power-stripped Loki. Karnilla accidentally instilled Wrecker and his crowbar with divine Asgardian power.