With The Black Panther Series coming to an end it might just be the right time to start over! With so many titles having reboots, regenesis and rebirths, It wouldn't be a bad idea at all!
Here's how I would go about it...
If I was writing his title I would temporarily end the Panther Cult in Wakanda and start the miniseries with the choice of a new one ( Lion, White Gorilla, Crocodile) Bast the panther Goddess showed up when Vibranium did and should leave with it now that there's no more! Have Shuri become the avatar of the chosen God so there's only one Black Panther.
This would force T'Challa and Storm to return home and when they would get there they would find the new Shuri with Chronok (her love interest) by her side. It would be explained that his futuristic technology is what has been keeping Wakanda's economy alive...
I would also reintroduce the Wakandan Secret Police to help facilitate her reign. After losing vibranium, Wakanda must be in chaos! Shuri is the kind of character that would sanction one.
When T'Challa and Storm find out about all this they are forced to reclaim the throne from ShuriChronok against the avengers and into a similar version to the one most people are (not) familiar with lol.Chronok who proves to be more resourceful than expected. Once they would have him cornered and go in for the final blow Shuri would die sacrificing herself to save her lover. It would be the perfect kind of tragedy to turn
Chronok disappears and T'Challa is king once more. His and Storms first actions as rulers is to abolish the monarchy and establish a democracy in Wakanda (which won't last too long). This is where issue one of the new "Black Panther & Storm" ongoing would pick up!