In issue #18, we'll be seeing Mr. Freeze out of Arkham Asylum and looking for revenge against the Court of Owls. Of course this will lead to conflict with the Birds of Prey and their new member, Strix. It seems that's not the only problem they'll be dealing with as we'll be seeing the introduction of The Daughters of the Dawn, who are abducting people with super powers. They'll be starting with a certain prisoner in Belle Reve.
Here's what Zubkavich said:
After being physically and emotionally trounced by Batman, Freeze is damaged goods and he’s not dealing with that too well. He feels he’s been used by Bruce Wayne, used by Batman and used by the Court of Owls. Since Batman and Wayne Corp. soundly kicked his ass, he’s lashing out at the next thing on his list and is determined to wreck vengeance on the Court and its many minions. That’s going to bring him into conflict with Strix and the rest of the Birds. The end result of that nasty conflict will be far reaching and bloody for everyone involved. Playing in the DC sandbox with both classic and new characters feels pretty cool, I don’t mind saying. When Freeze’s name came up during brainstorming sessions I felt I could build on the great new material that started in BATMAN ANNUAL #1. I’m excited about showing readers how focused and dangerous he can be.
You can read the full interview over at CBR.