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Dr. Maxilla Yale brings Anima back to the Tellus Institute to reunite with her mother. Both she and her mother continue to have dreams about a giant wolf named Fenris and Anima’s alter-ego Animus, and Yale experiments on a willing Anima to discover the truth about the dreams. Yale brings Anima to a spiritual location in the desert, where Yale tricks Anima into releasing Animus. However, in doing so, Animus is pulled from its native dimension Arkana, leaving the Fenris wolf alone fighting something called the Nameless One. In Arkana, the Nameless One kills Fenris, which also causes Willow Mason to be trapped in her dreams. Nameless One follows Animus to our world, where Anima and Animus fight Nameless One. Anima draws energy from Yale, causing her to age. Meanwhile, the battle attracts the attention of others, including Anima’s brother Jeremy, Agent Kyle Woodleaf, and other residents of Arkana. 

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