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Angel Blanco and his Brother Reynaldo Blanco
were drug lords who came under the eye of the New York City
police department. They were infiltrated buy under cover detectives Jane Vasco
and Maureen Fernandez
. The sting was going well until Maureen saw a news report that her husband was shot. Loosing control she fled the Blanco Brothers
leaving Jane holding the bag.
Jane was subjected to a bad batch of drugs to cause her pain and kill her. It ended up putting her in a coma for over a year. All that time her partner Maureen and Doctor Seth Hiller
took care of her. Finally Jane woke from her coma. Hiller claimed she had died by using a body of a Jane Doe To keep her safe from Angel and his brother.
Jane found that the drug gave her a high healing factor and she used this and trained her body again to face Angel and his brother Reynaldo. Under the new name Painkiller Jane she fought through the gang and ended up killing Reynaldo and shot Angel in the leg. She threatened to kill him if he ever came back to New York City. Angel left for a while but did come back to face Painkiller Jane again for the revenge of killing his brother.