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A man who would later take the name of Martin Li, was given an experimental drug which eventually allowed him control of some type of black electrical energy resembling a photographic negative.
A small time criminal that worked his way up to having his own crime family within the Maggia.
Edward Whelan was transformed by the second Baron Zemo into the hideous, beastly, rat creature that he is today.
Diablo is a 9th century alchemist with aspirations of world dominance. He is able to produce any number of amazing potions that defy scientific analysis. Diablo does not seem to age. He is an enemy of the Fantastic Four.
Molten Man is the stepbrother of Liz Allen. He has had several run-ins with Spider-Man. He was recently cured of his condition.
Ares is the son of Zeus and the Olympian God of War. After years of fighting against The Avengers, Thor, and mostly his own brother Hercules, Ares joined the ranks of the Avengers. He was a member of Tony Stark's official Avengers team and later Norman Osborn's Dark Avengers. After he attacked Osborn for tricking him in starting Siege on Asgard, he was stopped and killed by the Sentry.
Mary Jane Watson is an actress and a major love interest of Peter Parker aka Spider-Man. They have had a long and dramatic on-and-off-again relationship. She's one of the few people who know who he is and still supports him as a close friend and confidante.
Long time member of the Enforcers
Formerly a brilliant scientist, Jonathon Ohnn gained the ability to create teleportation portals when his research went wrong. Turning to a life of crime and adopting the moniker of 'The Spot', Ohnn has since become a semi-frequent adversary to Spider-Man and is oft treated as a less than serious threat despite his capabilities.
The Hypno-Hustler is a jive-talking black soul Disco singer who uses his goggles and evil boots of death to hypnotize music lovers, alongside his backup band, "The Mercy Killers."
A long time member of the Enforcers and one of the oldest foes of Spider-Man. Ox, as his name suggests, was the powerhouse of the team. There have been two people named Ox, they were brothers.
Former New York City Police Department officer and Peter Parker's ex-girlfriend. She was briefly transformed by the Goblin Serum, but has since been returned to normal.
Junkie who hangs out at the homeless shelter where May Parker volunteers.
A long-time member of the Enforcers and one of Spider-Man's oldest foes. Montana and his team ususally where hired by criminals to do 'criminal jobs'.
Harry Osborn's fiance who absorbed a unique variation of the Goblin Serum that allows her to shapeshift into a goblin. After losing those powers, she assumed the persona of Queen Cat.
A police officer in New York. Doesn't have faith that Spider-Man is a good guy.
The world's first "live streaming super-villain." She commits crimes to get more hits on her webpage.
One of Spider-Man's new Brand New Day villains, she has the power to flatten herself to the size of paper, as well as those she attacks. She is also has chameleon-like abilities, able to blend into any sort of scenery. She is obsessed with actor Bobby Carr.
A villain who uses nanites to alter motor vehicles to his liking. Formerly working for Mr. Negative, he is now a member of the Sinister Six.
The ultimate club girl of New York City.
The father of the former editor of The Daily Bugle, J. Jonah Jameson, and currently married to Peter Parker's Aunt May.
A journalist who worked at the Daily Bugle along with Peter Parker and after Civil War in Front Line newspaper. She seems to like sarcastic humor and Peter is usually the joke.
Michelle is the sister of Vin Gonzales and Peter Parker's former roommate.
He was a normal hippopotamus that was transformed into a humanoid hippopotamus by the High Evolutionary. His leg was bitten off by Mac Gargan/Spider-Man now he and other victims band together to destroy him.
The child of Menace.
One of Spider-Man's most dangerous enemies, the electric human dynamo known as Electro has constantly been a major threat for the Amazing Spider-Man.
Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
Doctor Octopus is a supervillain originating from Marvel Comics. A former nuclear physicist and atomic researcher, Otto Octavius' life changed forever when one of his experiments went horribly wrong involving his four mechanical appendages used to assist him in his experiments. From then on, Octavius soon after his initial encounter has become one of the most dangerous supervillains in the Marvel Universe.
J. Jonah Jameson is the former employer of Peter B. Parker and remains an aggravate of Spider-Man. He was once the chief editor and publisher of the Daily Bugle, a New York newspaper, and the mayor of New York before his resignation amidst scandal resulting from Superior Spider Man and the Goblin Nation. He now is a host of a show on the F.A.C.T. News Channel
During an experiment, Dr. Curtis Connors accidentally turned himself into a ferocious reptilian monster who seeks to turn humans into lizards like himself. The Lizard is one of Spider-Man’s oldest and deadliest foes while ironically, his alter ego is a close friend and former teacher of Spidey’s alter ego, Peter Parker.
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