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A synthetic adaptive android designed by the Mad Thinker to combat super-heroes. Although later defecting and becoming an employee of Goodman, Lieber, Kurtzberg and Holliway.
Former KGB operative known as the Crimson Dynamo and Airstrike. After primarily being an Iron Man villain, he's now a member of the Russian superhero team, the Winter Guard.
The Seventh Red Guardian and Leader of the Winter Guard. He is the Russian equivalent of Captain America.
A former Assistant District Attorney of New York City currently working at Nelson and Murdock law firm.
A clone of the original M.O.D.O.K. created by A.I.M. who currently works for S.H.I.E.L.D.
The infantile gorilla who replaced Mikhlo in the Super-Apes. He possesses the same superpower as his predecessor: super-strength.
Red Ghost's baboon capable of shapeshifting.
A cosmically empowered orangutan able to project magnetic force.
Former New York City Police Department officer and Peter Parker's ex-girlfriend. She was briefly transformed by the Goblin Serum, but has since been returned to normal.
As a child, Matt Murdock was blinded by radioactive waste while trying to save an elderly stranger about to get hit by a truck carrying the dangerous material. In turn, his other senses were heightened to superhuman sharpness and he gained a form of "radar sense". By day, he is a successful trial lawyer; but by night, he guards Hell's Kitchen as Daredevil: the Man Without Fear.
Ursa Major is a Russian mutant that transforms into a giant bear. He becomes a valuable member of the Soviet Super Soldiers and the Winter Guard.
Mary Jane Watson is an actress and a major love interest of Peter Parker aka Spider-Man. They have had a long and dramatic on-and-off-again relationship. She's one of the few people who know who he is and still supports him as a close friend and confidante.
Vanguard's fraternal twin sister. The first Darkstar, Laynia Petrovna is a mutant capable of manipulating an immeasurable amount of darkforce energy. She lived and died in service to her mother country Russia, but was later resurrected in the body of the previous Darkstar, Reena Stancioff, when Reena was transformed into a Dire Wraith.
The Jackal is an enemy of Spider-Man who played a big role in both of the Clone Sagas. He has since seemingly returned to infest Manhattan with spider-powers for his own sinister ends, organizing test subjects into a spider-powered army.
Secretary to J. Jonah Jameson.
Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
Swindled by his business partner out of his equal share of the profits from their company, Adrian Toomes set out for revenge by using a flying harness of his own design. He has however, met defeat several times at the hands of his arch-nemesis, The Amazing Spider-Man.
Dmitri Smerdyakov, AKA Chameleon, was first member of an inexperienced Spider-Man's rogue's gallery. The Chameleon is an elite spy and a master of disguise, using a variety of masks, technology, and other inventive techniques to flawless mimic the appearance and mannerisms of virtually anyone. Although he has been revealed to be the half-brother of Kraven The Hunter, the face behind his trade-mark white mask – worn even beneath his other masks – has never been seen.
Mysterio was a formidable foe to Spider-Man. So much so that his arts of illusion were carried on by others after the original Mysterio's death. The original Mysterio, Quentin Beck, has recently returned. The events behind his resurrection are currently shrouded in mystery.
Former enemy of Spider-Man and the Fantastic Four, Sandman reformed after realising he was unhappy with his life. He joined the Avengers and later Silver Sable's Wild Pack. Sandman eventually returned to crime after being brainwashed by the Wizard, but sometimes still displays desire to better himself.
An evil genius and leader of the Frightful Four.
One of Spider-Man's most dangerous enemies, the electric human dynamo known as Electro has constantly been a major threat for the Amazing Spider-Man.
An enemy of the Fantastic Four who has 3 superpowered apes at his disposal.
Phil Urich, was a hero who, somewhere along the line, began thinking the universe was against him, leading to a psychotic break. Formerly taking up the mantles of Darkhawk, Green Goblin and Hobgoblin, Urich is now known as the Goblin Knight.
A scientist who believes in predicting the future with math.
A career criminal, the man known as Rhino has incredible strength and durability. A long-time enemy of Spider-Man and the Incredible Hulk, Rhino isn't particularly malicious, and has tried on various occasions to leave behind his life of crime, but always seems to slide back into old habits.
The latest in a long line of warriors who wielded the power, Danny Rand is the immortal Iron Fist: protector of the mystical city of K'un Lun. He channels the soul of the dragon Shou-Lao making his fists into powerful weapons. He is among the best, if not the best fighter in the Marvel Universe. He has also been a member of The Defenders and the New Avengers.
Doctor Octopus is a supervillain originating from Marvel Comics. A former nuclear physicist and atomic researcher, Otto Octavius' life changed forever when one of his experiments went horribly wrong involving his four mechanical appendages used to assist him in his experiments. From then on, Octavius soon after his initial encounter has become one of the most dangerous supervillains in the Marvel Universe.
The Kingpin is a supervillain originating from Marvel Comics. The self-proclaimed kingpin of crime, Wilson Fisk is one of the most prominent figures of organized crime in the United States. He is the king of mobsters, controlling organized crime on the East Coast with an iron fist. Kingpin is a major enemy of superheroes Spider-Man and Daredevil.
Former cat burglar Felicia Hardy became a crime fighter when she became romantically attracted to and involved with Spider-Man. Felicia has the ability to instill "bad luck" around others - this comes in handy when fighting crime!
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