Character » Alistair Smythe appears in 109 issues.
Former pro baseball player who became a known criminal as the Boomerang. After fighting towards some semblance of redemption as a member of the Thunderbolts, he lead the seventh incarnation of the Sinister Six.
The very mention of his name makes lesser men tremble! The brilliant scientist whose iron mask conceals his scarred (but once handsome) face! Master of science and sorcery, Victor Von Doom is the monarch of Latveria, attempting the betterment of humanity through world conquest! Unequaled and unrivaled in every manner, Doctor Doom has had many conflicts with both earthly and cosmic super-beings, but he will always be known as the eternal nemesis of Reed Richards and his accursed Fantastic Four!
Doctor Octopus is a supervillain originating from Marvel Comics. A former nuclear physicist and atomic researcher, Otto Octavius' life changed forever when one of his experiments went horribly wrong involving his four mechanical appendages used to assist him in his experiments. From then on, Octavius soon after his initial encounter has become one of the most dangerous supervillains in the Marvel Universe.
Paula Crane, joined Smythe when her family business was destroyed by Jameson's expose.
Founder of the Brand Corporation.
The Kingpin is a supervillain originating from Marvel Comics. The self-proclaimed kingpin of crime, Wilson Fisk is one of the most prominent figures of organized crime in the United States. He is the king of mobsters, controlling organized crime on the East Coast with an iron fist. Kingpin is a major enemy of superheroes Spider-Man and Daredevil.
Otto Octavius' apprentice, who took the title of her mentor after Octavius' death, and has fought Spider-Man many times.
During an experiment, Dr. Curtis Connors accidentally turned himself into a ferocious reptilian monster who seeks to turn humans into lizards like himself. The Lizard is one of Spider-Man’s oldest and deadliest foes while ironically, his alter ego is a close friend and former teacher of Spidey’s alter ego, Peter Parker.
Former assistant of Mendel Stromm, designed Spider-Slayers for Alistair Smythe.
Mister E is an extradimensional entity from a realm known only as The Shadowverse. Though he looks like a living shadow Mister E's body is actually composed of lightweight dark matter.
A long-time archenemy of Captain America, Johann Schmidt is a proud Nazi general and the embodiment of evil, fear, and horror. He is known as the ruthless Red Skull.
MacDonald "Mac" Gargan was a failing private investigator that was turned into the Scorpion with financial help from J. Jonah Jameson. He became a host of the Venom symbiote and was part of Norman Osborn's Dark Avengers. After the US Government took the symbiote, he became The Scorpion once again.
When Shawna was fired from Daily Bugle after they discovered she had fabricated her story, she joined Smythe and let her be turned into one of the Swarm.
Silvio Manfredi has always been some kind of villain. His body is almost completly made up of cybernetic parts and he is almost like a human robot.
Spencer Smythe was a expert in robotics and created robots designed to kill Spider-man. He died due to radiation poisoning he received from the materials his robots were made of.
The Tinkerer is a Marvel character with an almost superhuman gift of genius in engineering, able to invent incredible gadgets from spare parts left lying around. His genius is comparable to the Fixer.
A genius chemist who invented a potent multi-polymer adhesive and immediately decided to use his invention to commit crimes. First assuming the identity of Paste-Pot Pete, he changed it to the more intimidating name of the Trapster.
Swindled by his business partner out of his equal share of the profits from their company, Adrian Toomes set out for revenge by using a flying harness of his own design. He has however, met defeat several times at the hands of his arch-nemesis, The Amazing Spider-Man.
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