Abraxas is the counterpart of Eternity and the embodiment of destruction. He was kept in check by Galactus.

He sought to destroy not only Earth-616, but all parallel realities as well, using the Ultimate Nullifier. However, the only being who knew its location was the Human Torch. Abraxas killed Galactus, and sent his head to Earth-616. When the Fantastic Four sought out the Watcher, they forgot who he was. Eternity told them it was caused by Abraxas.

After Mr. Fantastic gathered heroes to fight the minions of Abraxas on the moon, the Silver Surfer was killed by micro-organisms as he attempted to defend the Watcher from them. It was discovered that the possessed only part of the coordinates to the Ultimate Nullifier, but split between the minds of three other Human Torches in alternate universes.

After finding these alternate Human Torches, and passing on the information to the Human Torch of Earth-616, the Fantastic Four found the Ultimate Nullifier. However they were betrayed by the alternate version of Nova, who worked for Abraxas.

After Nova gave Abraxas the Ultimate Nullifier, Franklin Richards and Valeria Von Doom found out that Galactus wasn't dead, but inside the heart of Eternity. They restored Galactus but burnt out their powers. Galactus then recalled the Ultimate Nullifier from Abraxas' grasp. Galactus said that the Ultimate Nullifier was actually part of him. Due to interference from Nova, the Ultimate Nullifier fell to Mr. Fantastic, who realized that the only way to destroy Abraxas was to destroy and then recreate reality using the Nullifier. After he did, everyone who died, including the Silver Surfer, were brought back to life. Franklin Richards was left without any power, Valeria Von Doom was replaced with a new baby inside the womb of the Invisible Woman, and the Watcher was returned to normal.